A recent thread on Hacker News discussing Cloudflare Workers brought up an interesting item from Kenton Varda, tech lead for their Workers service ( # ):

On another note, currently we only support JavaScript, but we’re putting the finishing touches on WebAssembly support, which would let you run Go on Workers… stay tuned.

The context was using Go for Cloudflare Workers, but supporting WASM ( WebAssembly ) potentially opens the door to a broader range of programming languages.

There is a list at https://github.com/appcypher/awesome-wasm-langs with references for 30 different languages with projects to target WASM.